Risks of Cholesterol Drugs

May 11, 2011 · Posted in cholesterol · Comment 

How will history judge me for questioning the benefits of cholesterol-lowering drugs (CLDs)? I’ll never know, but a report in the British Medical Journal now says that the side effect of …

View full post on All Stories

Statins May Improve Blood Flow After Stroke

April 26, 2011 · Posted in cholesterol · Comment 

Cholesterol-lowering drugs known as statins may help clot-busting drugs treat strokes, according to researchers at Washington University School of Medicine in St. Louis. The research involved 31 patients with ischemic stroke, a disorder when a clot blocks blood flow to part of the brain. In 12 patients who were already taking statins to control their cholesterol, blood flow returned to the blocked areas of the brain more completely and quickly…

View full post on All Stories

Heart drug could cut pre-eclampsia threat

April 22, 2011 · Posted in cholesterol foods · Comment 

CHOLESTEROL-lowering drugs used to prevent heart disease in middle-aged men could prevent pre-eclampsia, scientists have said.

View full post on Health Stories

Statins May Raise Stroke Risk In Some: Study

January 12, 2011 · Posted in cholesterol foods · Comment 

People who have had a type of stroke caused by bleeding in the brain should avoid taking cholesterol-lowering drugs known as statins, U.S. researchers said on Monday….

View full post on Health Stories

Statins May Raise Stroke Risk in Some Patients

January 11, 2011 · Posted in cholesterol · Comment 

People who have had a type of stroke caused by bleeding in the brain should avoid taking cholesterol-lowering drugs known as statins

View full post on All Stories

Study finds statin use linked to rare autoimmune muscle disease

December 10, 2010 · Posted in cholesterol · Comment 

Johns Hopkins researchers have discovered how statins, the most commonly prescribed class of medication in the United States, appear to trigger a rare but serious autoimmune muscle disease in a small portion of the 30 million Americans who take the cholesterol-lowering drugs.

View full post on All Stories

American Heart Association Releases Updated Stroke Prevention Guidelines

December 3, 2010 · Posted in cholesterol · Comment 
David Goodhue – AHN News Reporter

Washington, D.C., United States (AHN) – Making healthy lifestyle choices can lower one’s risk of having a stroke by up to 80 percent, according to a new American Heart Association study.

The organization released its latest guidelines to stroke prevention this week, the first update since 2006.

The association said that making healthy lifestyle choices includes not smoking, eating a low-fat diet high in fruits and vegetables, drinking in moderation, exercising regularly and maintaining a normal body weight.

The highlights of the new guidelines also include:

  • Emergency room doctors should try to identify patients at high risk for stroke and consider making referrals, conducting screenings or beginning preventive therapy.

  • Although genetic screening for stroke among the general population isn’t recommended, it may be appropriate in certain circumstances, depending on family history and other factors.

  • The usefulness of stenting in persons who have a narrowing of a carotid artery in the neck as compared to an operation (endarterectomy) is still uncertain. Because of advances in standard medical therapies (including a change in lifestyle factors, treating high blood pressure and using antiplatelet and cholesterol lowering drugs) the usefulness of either procedure in people who have not had symptoms is unclear. Doctors must decide whether to perform either procedure on a case-by-case basis.

  • General population screening for carotid artery narrowing isn’t recommended.

  • Aspirin doesn’t prevent a first stroke in low-risk persons or those with diabetes or asymptomatic peripheral artery disease. However, it’s recommended for those whose risk is high enough for the reduction in stroke risk to outweigh the bleeding risks of aspirin.

Dr. Larry B. Goldstein, chairman of the American Heart Association’s statement writing committee and the director of the Duke University Stroke Center, said that between 1999 and 2006 there has been more than a 30-percent reduction in stroke death rates in the United States.

He said much of this reduction can be attributed to better prevention practices.

Article © AHN – All Rights Reserved

View full post on All Stories

Statin drugs cause liver damage, kidney failure and cataracts, says BMJ

November 7, 2010 · Posted in cholesterol foods · Comment 

(NaturalNews) Cholesterol-lowering statin drugs significantly increase a person’s risk of cataracts, muscle weakness, liver dysfunction and kidney failure, according to a study in the British Medical Journal . The study also confirmed that the drugs lower the risk of heart disease and esophageal cancer, but claims of other health benefits were unsupported. Researchers from Nottingham University in the United Kingdom examined data on more than 2 million patients between the ages of 30 and 84, seen at 38 different general practices, who had been prescribed the cholesterol-lowering drugs. More than 70 percent were taking simvastatin (Zocor), 22.3 percent were taking atorvastatin (Lipitor), 3.6 percent were taking pravastatin (Pravachol, Selektine), 1.9 percent were taking rosuvastatin (Crestor) and 1.4 percent were taking fluvastatin (Canef, Lescol, Lochol, Vastin). The researchers confirmed prior data suggesting that statins increase patients’ risk of cataracts, liver dysfunction, kidney failure and a form of muscle weakness known as myopathy. They found that for every 10,000 women treated with the drugs, 23 would develop acute kidney (renal) failure, 39 would develop myopathy, 74 would develop liver dysfunction and 309 would develop cataracts. Men suffered an even higher risk of myopathy, but their risks of the other three conditions were similar to those suffered by women. Putting it in different terms, the researchers found that only 434 people would need to be treated with the drugs for five years for one case of acute renal failure to develop. It would take only 136 treated for each case of liver dysfunction and 33 for each case of cataracts. Among women, 259 would need to be treated for each case of myopathy; among men, the number was only 91. The risk of developing all conditions was highest during the first year of treatment, but continued throughout the course of the study. Risk of liver and kidney problems increased proportionally with the dose of statins being taken. All drugs appeared to pose a similar risk of all conditions, with the exception of fluvastatin, which increased the risk of liver dysfunction more than its competitors. Men taking fluvastatin were twice as likely to develop liver dysfunction as those not taking statins, while women’s risk increased by 2.5 times. The researchers did find, however, that the risk of cataracts returned to normal within one year of stopping statin treatment, while the risk of liver and kidney problems returned to normal within one to three years. Additionally, they found no connection between statin use and the risk of dementia, osteoporotic fracture, Parkinson’s disease, rheumatoid arthritis or venous thromboembolism. Examining the purported benefits of the drugs, researchers found that they did in fact lower the risk of heart disease, averting 271 cases for every 10,000 high-risk patients treated. Put another way, 33 high-risk men or 37 high-risk women would need to be treated with the drugs to avert one case of the disease. Although advocates of the drugs have claimed that they may also reduce the risk cancer, the researchers found almost no data supporting these claims. The study “largely confirmed other studies that reported no clear association between statins and risk of cancers,” the researchers wrote. The only cancer-fighting effect uncovered in the study was a slightly lower risk of esophageal cancer, with eight cases averted for every 10,000 high-risk women treated. In other words, 1,266 high-risk women or 1,082 high-risk men would need to be treated with the drugs to prevent one case of esophageal cancer. Although sales of the blockbuster drugs are unlikely to be reduced as a result of the study, the researchers encouraged closer monitoring of patients for side effects and said their findings “would tend to support a policy of using lower doses of statins in people at high risk of the adverse event.” Sources for this story include: http://www.reuters.com/article/idUSTRE64J7B820100520; http://www.medpagetoday.com/Cardiology/Atherosclerosis/20232.

View full post on Health Stories

There is a Drugfree Way to Lower Cholesterol

August 20, 2010 · Posted in cholesterol · Comment 

There has been a substantial increase in people having high cholesterol levels. It has been proven in many studies that an unhealthy increase in blood cholesterol levels can lead or be associated with the development of heart disease. High cholesterol levels can also increase the risk of strokes and heart attacks. Coronary heart disease is the leading cause of death among people living in industrialized societies such as the US. The increasing incidence of high cholesterol levels in people living in this part of the world can often be contributed to a high saturated fat diet, smoking and leading a sedentary lifestyle.

There are several dugs now available that is being used to treat unhealthy cholesterol levels in people. Most popular of these is the HMG-CoA Reductase Inhibitor or what is more simply known as Statins. This group of cholesterol lowering drugs come in different name drugs and is increasingly being used in order to help high risk patients drastically lower their cholesterol levels. Statins can also increase the levels of HDL or “good” cholesterol.

Although statins and other known drugs being used to lower cholesterol levels have been proven to be very effective, there are also other ways available for people to lower their cholesterol levels without the use of such drugs. One of these is trying to lead a more active lifestyle. Physical activity and exercise is an important part of several low cholesterol therapies that aim to reduce bad cholesterol levels. Regular exercise can also help in reducing blood pressure, excess weight as well as decrease the diabetes risk.

Following a low cholesterol diet can also help a lot in trying to decrease high cholesterol levels. Scientists have found that a low cholesterol diet can help decrease cholesterol levels by as much as 29 percent in one month. This suggests that a combination diet can also be as effective as drugs like statins used to treat people with high cholesterol levels. It has also been established that eating low cholesterol and high fiber foods can cut individual cholesterol level by seven percent.

A recommended diet that can help people avoid developing coronary heart disease include consuming non-hydrogenated or unprocessed fats, eating a rich diet of soy protein, nuts and fiber rich foods such as oats and barley. Increased consumption of Omega-3 fats from fish and other plant sources can also have a positive effect in any low cholesterol diet as well as a healthy amount of fruits and vegetables.

Information on cholesterol ratio can be found at Cholesterol Guidelines.

One Reason High Cholesterol is a Bad Idea: Death

December 3, 2009 · Posted in cholesterol · Comment 

The truth? You cant handle the truth! Here’s some information you need to know:

Any total cholesterol level above 200 milligrams per deciliter of blood (written mg/dL) is considered borderline high. Extremely high total cholesterol is any reading above 240 mg/dL and one that puts you at risk for heart disease, liver failure, and other health problems. And here is why Americans are at serious risk:

  • 107 million, or 1 in 5 adults, has cholesterol levels above 200 mg/dL.
  • Almost 38 million more have levels above 240 mg/dL.
  • More women over age 45 have high cholesterol than men.
  • Almost 30 million prescriptions are written each year for cholesterol lowering drugs, accounting for $20 billion in annual sales for the pharmaceutical industry.
  • Americans spend $10 billion per year on the statin drug, Lipitor alone
  • In 2001, the statin drug, Baycol used to lower cholesterol was taken off the market due to toxic side effects.
  • Most drugs prescribed today to lower cholesterol are statin drugs.
  • Asians on average have an LDL cholesterol level of less than 95 because of their low fat diet. Anything under 100 for LDL cholesterol is considered good.
  • Diet and lifestyle changes, without the use of drugs, have been shown to decrease LDL cholesterol in one years time by 40 percent on average (from 144 down to 87 mg/dL.)

Q: What is cholesterol?

A: Cholesterol is a fatty substance present in most meaty foods and some vegetables. In normal amounts it is an important building block of bile acids, which help digestion, and steroid hormones. In the blood, cholesterol is found in particles containing both lipids (fats) and proteins; hence they are referred to as lipoproteins.

Q: Who should be tested for high cholesterol?

A: Maintaining healthy cholesterol levels is important for everyone: young, middle-aged, and older adults; women and men; and people with or without heart disease. Adults 20 years and older should have their cholesterol measured at least once every 5 years. Those found to have elevated cholesterol requiring changes in diet or drug therapy, or who have been diagnosed with heart disease will require more frequent lipid profile testing, at least annually.

Q: Why should I test my cholesterol level?

A: As one of the major risk factors for developing heart disease, your blood cholesterol level affects your chances of having a heart attack. It is important to find out what your cholesterol levels are because lowering cholesterol levels that are too high lessens the chance of having a heart attack or dying from heart disease, even if you already have it.

Q: Besides cholesterol, what are other risk factors for heart disease?

A: Cholesterol is only one risk factor that may lead to heart disease. The other major risk factors are listed below. Your doctor can help you to understand your risk for heart disease by taking into account these other factors along with your cholesterol.

  • Cigarette smoking
  • High blood pressure
  • Early heart disease in a close relative (before age 55 in men & 65 in women)
  • Age more than 45 for men or 55 for women
  • LDL and HDL cholesterols
  • Life habit risk factors (obesity, physical inactivity and fatty diet)

Q: What is LDL?

A: Often called “bad cholesterol,” LDL is the main source of cholesterol build-up and blockage in the arteries.

Q: What is HDL?

A: Often called “good cholesterol,” HDL helps keep cholesterol from building up in the arteries.

How does cholesterol cause heart disease? When there is too much cholesterol (a fat-like substance) in your blood, it builds up in the walls of your arteries. Over time, this buildup causes “hardening of the arteries” so that arteries become narrowed and blood flow to the heart is slowed down or blocked. The blood carries oxygen to the heart, and if enough blood and oxygen cannot reach your heart, you may suffer chest pain. If the blood supply to a portion of the heart is completely cut off by a blockage, the result is a heart attack.

High blood cholesterol itself does not cause symptoms; so many people are unaware that their cholesterol level is too high. It is important to find out what your cholesterol numbers are because lowering cholesterol levels that are too high lessens the risk for developing heart disease and reduces the chance of a heart attack or dying of heart disease, even I you already have it. Cholesterol lowering is important for everyone-younger, middle age, and older adults; women and men; and people with or without heart disease.

Everyone age 20 and older should have their cholesterol measured at least once every 5 years. It is best to have a blood test called a “lipoprotein profile” to find out your cholesterol numbers. This blood test is done after a 9 to 12 hour fast and gives information about your:

  • Total cholesterol
  • LDL (bad) cholesterol
  • The main source of cholesterol buildup and blockage in the arteries
  • HDL (good) cholesterol
  • Helps keep cholesterol from building up in the arteries
  • Triglycerides
  • Another from of fat in your blood

Saturated Fat & Cholesterol an evil combination

If you are trying to control you blood cholesterol level, you must limit not only the amount of cholesterol you consume, but also the amount of saturated fat, which appears to stimulate the body’s production of cholesterol.

Although they’re often mentioned together, cholesterol and fat is not the same thing. Cholesterol is found only in animal products – meats, poultry, dairy products, and eggs.

Steps you can take to keep your cholesterol level down:

Substitute unsaturated fats for saturated fats

Polyunsaturated fats (such as safflower and corn oil) and monounsaturated fats (such as olive oil) help to lower blood cholesterol levels.

But this doesn’t mean you should add any of these fats to your diet – you should still keep your total fat intake at or below 30 percent of your daily calories. Replace butter in cooking with olive or corn oil. Substitute fish for some of the red meat and poultry in your diet.

Lose weight, if necessary

Not only does excess body fat raise your total blood cholesterol and LDL levels, but it also is an independent risk factor for heart disease. On average, each two pounds of excess body fat contributes one mg//dL of total cholesterol.

Exercise

A program of regular aerobic exercise may help lower total cholesterol and raise HDL. To get this benefit, as well as the other benefits exercise offers, you should exercise at least three times per week for thirty minutes a session.

Increase your consumption of food high in soluble fiber

Oat bran is certainly the most familiar of these food along with legumes and other vegetables, such as black-eyed peas, kidney beans, sweet potatoes, zucchini, and broccoli. In the fruit category, bananas, apples, pears, and oranges have some soluble fiber.

Don’t Smoke

Smoking increases total cholesterol and reduces HDL, and is an independent risk factor for heart disease as well.

Author: Ian Mackie
Article Source: EzineArticles.com

Powered by Yahoo! Answers