Discovery Of ‘Master Switch’ Gene For Obesity And Diabetes

May 15, 2011 · Posted in cholesterol · Comment 

A team of researchers, led by King’s College London and the University of Oxford, have found that a gene linked to type 2 diabetes and cholesterol levels is in fact a ‘master regulator’ gene, which controls the behaviour of other genes found within fat in the body. As fat plays a key role in susceptibility to metabolic diseases such as obesity, heart disease and diabetes, this study highlights the regulatory gene as a possible target for future treatments to fight these diseases…

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About Hypothyroidism – a Common Health Problem

February 9, 2011 · Posted in diets to lower cholesterol · Comment 

By hypothyroidism, the thyroid gland is producing too less hormones to stimulate the metabolism, or the body is not able to utilize the hormones. The lack of thyroid hormones slows down the metabolism and thus all the activities in the body, giving a combination of many symptoms related to slowness of bodily processes.

Hypothyroidism is common, but the frequency of the condition is not well determined. Some authorities estimate that 0.5% of the total American population have the disease to some degree. The frequency is much greater among people over 50 years of age than among young people.

THE SYMPTOMS AND COMPLICATIONS OF HYPOTHYROIDISM

The most common early symptoms are: Mental and physical fatigue, weakness, weight gain or over-weight, and depression.

One or more of these symptoms also use to appear early: Constipation, sensitivity to coldness, cold hands and feet, thick tongue, decreased sweating, dry hair, thin brittle hair, thin brittle nails, muscle and joint pain, pale or yellowish skin, rashes and itching.

One or more of these symptoms usually appear later: Poor memory, slow thought process, drowsiness, slow speech, thinning of eyebrows, hoarseness, low blood pressure, poor circulation, dry and flaky skin, decreased taste and smell, menstrual irregularities, skin thickening, puffy face, puffy hands and feet, swelling of extremities, overall swelling, muscle spasms, muscle atrophy, joint stiffness.

In children or young persons hypothyroidism may give developmental problems, like disturbed tooth development and short stature.

Hypothyroidism increases the risk of elevated cholesterol levels, heart disease and diabetes (diabetes mellitus). This occurs even by moderately decreased thyroid production.

THE THYROID GLAND AND ITS HORMONES

To understand the hypothyroidism, some knowledge about the thyroid gland and its hormones is essential.

The thyroid gland produces hormones that accelerate and in other wise regulate metabolism. A part of metabolism is the process of breaking down energy containing nutrients, and using the energy to produce molecules that all the processes and activities in the body use as fuel. Another part is the production of molecules that the body use as building materials.

The thyroid makes four hormones: Thyroxin (T4), triiodothyronine (T3), diiodothyronine (T2) and monoiodothyronine (T1). The hormones contain iodine, and the figures tell about the number of iodine atoms in each hormone molecule. T3 is not made directly, but is produced from T4. T3 is a more efficient hormone than T4. Therefore this conversion is important.

The pituitary, a gland under the brain, produces a hormone called thyrotropin or thyroid stimulating hormone (TSH) that enhances the activity of the thyroid gland. If the body has too less thyroid hormone in the blood, the pituitary produces more thyrotropin. This makes the thyroid gland speed up its own production. By a too heavy thyroid hormone concentration, less thyrotropin is produced by the pituitary, and the thyroid gland slows down. This feed-back mechanism regulates the metabolism of the whole body.

THE MECHANISMS AND CAUSES OF HYPOTHYROIDISM

By hypothyroidism the body does not get enough thyroid hormone, or the hormones do not work effectively in the body. This causes the metabolism to slow down. When the metabolism decreases, the processes in the body do not get enough fuel and building materials, and all the body activities will therefore slow down. Energy containing nutrient will also be stored as fat, since they are not broken down.

Serious variants of hypothyroidism are called myxedema. This is a rare condition. However, less serious, but painful variants are common. There are several reasons for hypothyroidism, each giving a variant of the disease:

*An autoimmune reaction against the thyroid tissue can destroy the capability of the thyroid gland to produce hormones (for example Hashimoto’s disease).

*Sometimes the production of T3 by conversion from T4 is impaired. The total amount of hormones may be normal in these cases, but the body is still lacking T3, and gets the symptoms of hypothyroidism.

*Iodine deficiency can cause hypothyroidism, since the thyroid hormones contain iodine. In Europe and America the food is seldom short in iodine, but bad nutrition may result in iodine deficiency.

*Surgery or radiation at the thyroid area can destroy enough tissue to cause hypothyroidism.

*Injury or disease in the pituitary or of the part of the brain controlling the pituitary may cause a decrease in secreted thyrotropin, and then the thyroid will respond by producing less of its own hormones with hypothyroidism as a result.

*Some people have symptoms of hypothyroidism even though the amount of thyroid hormone in the blood is normal. One of the symptoms is raised levels of thyrotropin, indicating that the body signals need for more thyroid hormones. This variant may be caused by conditions elsewhere in the body that make it difficult for the hormone to reach their destination in the cells. In many of these cases the immune system produces anti-bodies against the thyroid hormones. This variant is called sub-clinical hypothyroidism, and responds to the same treatment as ordinary hypothyroidism.

*Some types of food can contribute to a depressed thyroid function or aggravate hypothyroidism when eaten raw in great amounts: Brussel sprouts, broccoli, corn oil, cabbage, cauliflower, kale, kohlrabi, radishes, rutabaga, soy and turnips. By cooking these vegetables, the depressing effect is decreased

*Factors suspected for causing hypothyroidism are: The artificial sweetener aspartame, mercury pollution, dental fillings containing mercury, fluoride and heavy metal pollution.

HOW CAN HYPOTHYROIDISM BE TREATED

For serious hypothyroidism caused by tissue destruction, external supplement of thyroid hormones is necessary.

When the condition is caused by lack of iodine in the diet, dietary changes and iodine supplements will be a part of the treatment.

Less serious, but painful hypothyroidism is sometimes also treated with hormone supplements. In these cases it is difficult to find the right dose, and treatment may result in hormone poisoning.

You can sometimes alleviate hypothyroidism by reducing the amount of food suspected for depressing the thyroid function: Brussel sprouts, broccoli, corn oil, cabbage, cauliflower, kale, kohlrabi, radishes, rutabaga, soy, soy products and turnips. However, these food types are valuable in many ways, so it is probably not wise to cut them out totally. Also try to avoid artificial ingredients like the sweetener aspartame, conserving additives and fluoride.

Changing out mercury dental fillings and avoiding mercury or heavy metal exposure may help to ameliorate the condition.

You may also alleviate the condition by eating food that stimulates the thyroid function according to practical experience: Chia seed, dulse, fish from the ocean, flax seed, pumpkin seed, seaweed, coconut and brewer yeast.

You can find nutritional supplements to help for hypothyroidism. The compositions of these products vary:

*They may contain building materials that the thyroid uses to make its hormones, for example: iodine, acetyl-L-tyrosine or L-phenylalanine.

*They may also contain vitamins and minerals that stimulate the mechanism of hormone production by being a part of necessary enzymes, or by helping the absorption of the ingredients that hormones are made from, like: Magnesium, zinc, selenium, copper and vitamin E.

*They may furthermore contain constituents that stimulate tissue regeneration by being part of tissue building enzymes, and thus helping to restore a degraded thyroid, for example: Folic acid or folate, vitamin B2 (riboflavin), B3 (niacin), B5 (pantothenic acid or pantothenate), B6 (pyridoxine), B12 (cyanocobalamin) and molybdenum.

Knut Holt PhotoAbout Author
Knut Holt is an internet consultant and marketer focusing on health items. To find more advices and natural products to help against hypothyroidism and other health problems please visit:

http://www.panteraconsulting.com

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Lowering Cholesterol Through Eating Right

June 25, 2010 · Posted in cholesterol · Comment 

Although most people believe that the trend towards cutting off cholesterol in diets is brought on by the fact that the young generation is dieting themselves to death; it is not so. Limiting the body’s cholesterol levels is not only for appearance’s purposes but also for health reasons. Cholesterol levels in the body, when at a certain level, can cause a host of body complications and disease that can even eventually cause death.

Problems like hypertension, heart disease, and diabetes come in mind. This is especially true with people who are already old and in their middle ages because of the slowing down of the bodily processes particularly the digestive system and the body’s ability to convert fats to energy. This is perhaps why most older people, especially those that have weight issues, are being asked by their doctors to lessen their cholesterol intake.

What is cholesterol?

People have been talking about cholesterol but do they what it is and how it affects the body. Because of news about rising cases heart problems in the country, cholesterol has become an overnight antagonist. Everybody thinks that cholesterol is bad.

Actually, not all cholesterol is bad for the body. In fact, our bodies need cholesterol to make bile salts. It is also a major ingredients in maintaining hormonal balance as well as in the production of Vitamin D. Things become troubled when the levels become too high that the cholesterol already clog the arteries, making it hard for the blood to flow and the heart to pump.

There are two kinds of cholesterol, the good and the bad. The LDL, which is the bad kind, adhere to the arterial walls, forming plaques that eventually clog the passageway. Saturated fats and the trans fatty kind are sources of this kind of cholesterol. This is frequently found in pre-packed foods like potato snacks and canned goods.

The HDL, on the other hand, can lower the levels of LDL cholesterol. This is because the good HDL helps transport the LDL cholesterol from the arterial walls back to the liver where it is excreted out. These are found in nuts and in seafood particularly fishes.

People who want to lower their LDL levels are also advised to eat a lot of fruits because of the fiber that they bring to the body. Oats, cereals, and legumes are also great sources of fibers that can help combat the rise of LDL cholesterol, eventually decreasing the risk of heart disease.

Factors that affect cholesterol levels

Contrary to popular opinion, it is not just the diet that should be taken into consideration when dealing with high cholesterol levels. There are actually a lot of factors that affect the condition. One of these is the age and the gender. Older people are more affected by increased levels of cholesterol because of their bodies’ slowing processes. Another factor is the level of physical activity. Exercise can actually help in lowering down of LDL cholesterol. Also, it can help in strengthening the body and in toning the muscles.

Lowering cholesterol levels

From what was mentioned above, it seems remarkably simple to lower the body’s cholesterol levels… that is if one has the discipline to see it through. Just eat right and exercise regularly, avoid canned and pre-packed foods and you are on your way to lower cholesterol levels.

Visit Cholesterol Guidelines to learn about normal cholesterol levels and high cholesterol foods.

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